At the conclusion of this activity, participants will be able to list and recognize life-threatening causes of chest pain. The learner will be able to carry out a focused history and physical examination for the patient presenting with chest pain. Furthermore, the learner will be able to list relevant investigations to order for patients with chest pain, including an ECG and imaging, and analyze the information from these investigations to narrow down the differential diagnosis. Finally, participants will acquire knowledge in managing patients presenting with the most life-threatening causes of chest pain. This activity will allow participants to be comfortable in the assessment of any patient presenting to chest pain in the clinic or hospital setting.